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Olopatadine blocks histamine action by binding to histamine receptors on the conjunctiva (membrane covering the white part of the eye or sclera) of the eye as well as blocking histamine release from mast cells in the eye.

Subsequently, “intermittent” and “persistent” are not precisely synonymous with seasonal and perennial allergic rhinitis.

Research methodology For the systematic review of bilastine data, a Pub Med search was undertaken of all publications including “bilastine” in the title and/or abstract. All preclinical and clinical trials were assessed for inclusion in the review.